Cardiovascular Biomaterials and Blood Compatibility

Timeslot: Wednesday, April 3, 2019 - 1:00pm to 3:00pm
Track: Cardiovascular Biomaterials
Room: Yakima 2


Thrombosis is often a major concern with cardiovascular medical devices such as stents, vascular grafts, heart valves, pacemakers, defibrillators, ventricular assist devices, cardiopulmonary bypass, and artificial heart. Although significant progress has been made in developing and using a wide variety of metallic, polymeric, ceramic, and natural biomaterials for making cardiovascular medical devices, still the blood compatibility of these devices remains an issue. This general session will focus on (i) recent developments in cardiovascular biomaterials for improving blood compatibility; (ii) the development of novel biomaterials for applications in cardiovascular medical devices; (iii) novel coatings and surface modification technologies for improving blood compatibility; (iv) in vitro and in vivo evaluation of blood compatibility of biomaterials; (v) clinical evaluation of cardiovascular medical devices; (vi) novel approaches to improve endothelialization of cardiovascular implants and devices; (vii) interactions of vascular cells with biomaterials


Abstracts will be available for download on April 3, 2019.

  • 1:00:00 PM 29. Prevention of Acute Venous Stent-induced Thrombosis Using Inhibition of FXII, M. Hinds*(1), K. Nguyen(1), M. Wallisch(1,2), J. Johnson(1), A. Gruber(1,2); (1)Oregon Health & Science University, Portland, OR, USA, (1)Oregon Health & Science Unversity, Portland, OR, USA, (2)Aronora, Inc., Portland, OR, USA

  • 1:15:00 PM 30. In vitro Dynamic Thrombogenicity Testing of Biomaterials: Impact of Test Sample Length and Flow Loop Configuration, M. Jamiolkowski*, M. Golding, R. Malinauskas, Q. Lu; US Food and Drug Administration, Silver Spring, MD, USA

  • 1:30:00 PM 31. Inorganic Polymerization for Crosslinking Porcine Pericardium as Bioprosthetic Heart Valves with Improved Extracellular Matrix Stability and Biocompatibility, G. Guo*, L. Jin, W. Jin, Y. Lei, Y. Wang; National Engineering Research Center for Biomaterials, Chengdu, China

  • 1:45:00 PM 32. Correlating Thrombus Constituents of Surface-Modified Vascular Graft Materials to Luminal Volume Using MicroCT to Better Quantify Clinical Functionality, D. Anderson*, A. Gupta, M. Hinds; Oregon Health & Science University, Portland, OR, USA

  • 2:00:00 PM 33. Enhanced Biocompatibility of Stents via CD47 Surface Functionalization, V. Inamdar*, E. Fitzpatrick, I. Alferiev, C. Nagaswami, R. Levy, I. Fishbein, S. Stachelek; Children's Hospital of Philadelphia, Philadelphia, PA, USA

  • 2:15:00 PM 34. Biodegradable, Elastic Polyurethane with Enhanced Anti-Thrombogenicity as Blood-Contacting Biomaterials, C. Xu*(1,2), A.E. Kuriakose(1,2), D. Truong(1,2), P. Punnakitikashem(1,2), K.T. Nguyen(1,2), Y. Hong(1,2); (1)University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA, (2)University of Texas at Arlington, Arlington, Arlington, TX, USA

  • 2:30:00 PM 35. Engineering Ubx-based Materials to Promote and Guide Neovascularization, G. Geraldo Mendes*, D. Howell, S.-P. Tsai, K. Bayless, S. Bondos; Texas A&M Health Science Center, College Station, TX, USA

  • 2:45:00 PM 36. Sustained Release of Synthetic Glycopolymers for Enhanced Endothelialization of Electrospun Scaffolds, S. Jiang*, J. Wu, Y. Hang, Q. Liu, D. Li, H. Chen; State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials, Suzhou, China