Biomaterials for Therapeutic Drug Delivery Rapid Fire

Timeslot: Wednesday, April 3, 2019 - 3:15pm to 4:45pm
Track: Therapeutic Delivery
Room: Skagit 2

About

Controlled release approaches have the potential to effectively treat a variety of medical conditions, while avoiding complications such as off-site toxicity and drug-resistance. Approaches can include localized, depot-based methods as well as targeted, systemic treatments. Controlled drug delivery can result from affinity interactions, bond cleavage, reservoir or diffusion-based control, and/or stimulus-responsive methodologies. This session will focus on the development of these drug delivery systems, which include nano and microparticles, hydrogels, scaffolds, and thin films, for applications including but not limited to regenerative medicine/tissue engineering, cancer, microbial infection, and autoimmune diseases.

Abstracts

  • 3:15:00 PM 57. Nanoengineered DNA-based Injectable Hydrogels as Sustained Drug Delivery Platform for Cranial Defect Repair, S. Basu*(1), S. Pacelli(1), A. Paul(1), Y. Feng(2), Q. Lu(2), J. Wang(2); (1)University of Kansas, Lawrence, KS, USA, (2)University of Kansas Medical Center, Kansas City, KS, USA

  • 3:20:00 PM 58. Design of Biocompatible Crosslinkers for Tuning Hydrolytic Degradation of Polyethylene Glycol Hydrogels, S. Kroger*, L. Hill, S. Zustiak; Saint Louis University, St. Louis, MO, USA

  • 3:25:00 PM 59. Biosensitive Hydrogel Depot with Rapid and Long-Term Drug Delivery Efficacy, P. Dosta Pons*(1,2), N. Artzi(1,2,3), E. Zhang(1,2), J. Conde(1,2); (1)Brigham and Women's Hospital, Cambridge, MA, USA, (2)Institute for Medical Engineering and Science, Cambridge, MA, USA, (3)Broad Institute of Harvard and MIT, Cambridge, MA, USA

  • 3:30:00 PM 60. Controlled Release of Anti-inflammatory and Pro-angiogenetic Agents via Microbeads Scaffolds, J. Liang*, K. Jiang, R. Accolla, C. Stabler; University of Florida, Gainesville, FL, USA

  • 3:35:00 PM 61. Dual Release of Anti-Inflammatory and Anti-Microbial Drugs from Affinity Polymer Coated Sutures, R. Haley*(1), V. Qian(2), G. Learn(1), H. von Recum(1); (1)Case Western Reserve University, Cleveland, OH, USA, (2)University of California, Berkeley, Berkeley, CA, USA

  • 3:45:00 PM 62. Cellular Effects of Carbon Monoxide Releasing Poly(diol-citrate) Polymers, A. Webb*, D. Lichlyter, B. James; University of Florida, Gainesville, FL, USA

  • 3:50:00 PM 63. In Situ Integration of Electrospun Fibers with Microneedles, R. Creighton*, J. Phan, K. Woodrow; University of Washington, Seattle, WA, USA

  • 3:55:00 PM 64. Design of an Affinity Based Cytokine Release System to Temporally Control Macrophage Behavior, E. Lurier*(1,2), A. Smits(2), C. Bouten(2), K. Spiller(1); (1)Drexel University, Philadelphia, PA, USA, (2)Eindhoven University of Technology, Eindhoven, Netherlands

  • 4:00:00 PM 65. Mitigate Hydrophobicity-Induced Immunogenicity using Biocompatible Sugar Poly(orthoester), W. Du*, S. Maiti; Central Michigan University, Mount Pleasant, MI, USA

  • 4:05:00 PM 66. Single Application Thixotropic Antibiotic Delivery Systems for Otitis Externa, M. Serban*(1), B. Serban(1), J. Alverson(2), N. Priestley(2), E. Arrigali; (1)University of Montana - BMED, Missoula, MT, USA, (2)University of Montana - Chemistry, Missoula, MT, USA

  • 4:15:00 PM 67. Parallel Evaluation of Two Promising Immunoisolation Strategies for Beta Cell Replacement: Conformal Coating Versus Double Alginate Encapsulation, T. De Toni*(1), A. Stock(1), S. Safley(2), C. Weber(2), O. Alcazar(1), P. Buchwald(1), A. Tomei(1); (1)University of Miami, Coral Gables, FL, USA, (2)Emory University, Atlanta, GA, USA

  • 4:20:00 PM 68. Islet-like Microtissues with Toroidal Geometry for Enhanced Cellular Viability, Y. Chen*, D. Nguyen, Y.X. Wong, T. Dang; Nanyang Technological University, Singapore, Singapore

  • 4:25:00 PM 69. Thermosensitive Magnetic Liposomes for Dual Targeted Stimuli-Responsive Drug Delivery in Glioma Treatment, J.-P. Chen*(1), H.-L. Hsu(1), Y.-J. Lu(2); (1)Chang Gung University, Taoyuan, Taiwan, (2)Chang Gung Memorial Hospital, Toayuan, Taiwan

  • 4:30:00 PM 70. Controlled Cell Migration Within Cell Selective Hydrogels, E. Pashuck*(1,2), S. Fung(1), N. Joshi(1), J. Kohn(1); (1)Rutgers University, Piscataway, NJ, USA, (2)Lehigh University, Bethlehem, PA, USA

  • 4:35:00 PM 71. Local Delivery of Epigenetically Stimulating Folic Acid For Peripheral Nerve Regeneration, J. Yang*, G. Kim; Pennsylvania State University, University Park, PA, USA