Biomaterials for Therapeutic Drug Delivery 2

Timeslot: Saturday, April 6, 2019 - 10:30am to 12:30pm
Track: Therapeutic Delivery
Room: Skagit 4/5


Controlled release approaches have the potential to effectively treat a variety of medical conditions, while avoiding complications such as off-site toxicity and drug-resistance. Approaches can include localized, depot-based methods as well as targeted, systemic treatments. Controlled drug delivery can result from affinity interactions, bond cleavage, reservoir or diffusion-based control, and/or stimulus-responsive methodologies. This session will focus on the development of these drug delivery systems, which include nano and microparticles, hydrogels, scaffolds, and thin films, for applications including but not limited to regenerative medicine/tissue engineering, cancer, microbial infection, and autoimmune diseases.


Abstracts will be available for download on April 3, 2019.

  • 10:30:00 AM 465. Locally Anchoring Proteins to Target Tissues via Fusion to Galectin-3, S. Farhadi*, E. Bracho-Sanchez, M. Fettis, D. Seroski, S. Freeman, B. Keselowsky, G. Hudalla; University of Florida, Gainesville, FL, USA

  • 10:45:00 AM 466. Pulmonary Nanoparticle Delivery to Ameliorate Neuroinflammation of Experimental Autoimmune Encephalomyelitis, E. Saito*, S. Gurczynski, K. Kramer, C. Wilke, B. Moore, L. Shea; University of Michigan, Ann Arbor, MI, USA

  • 11:00:00 AM 467. Affinity Based Release of Protein Therapeutics to Treat Retinitis Pigmentosa, C. Teal*, V. Delplace, A. Ortin-Martinez, S. En-Leh Tsai, V. Wallace, M. Shoichet; University of Toronto, Toronto, ON, Canada

  • 11:15:00 AM 468. Liver Targeted Primaquine Drugamers for the Treatment of Malaria in High Risk Settings, S. Srinivasan*(1), J. Conner(2), R. Rochford(2), K. Montgomerry(1), C. LeGuyader(1), F. Su(1), P. Stayton(1), A. Convertine(3); (1)University of Washington, Seattle, WA, USA, (2)University of Colorado, Aurora, CO, USA, (3)Missouri University of Science an

  • 11:30:00 AM 469. Non-Invasive, Epicortical Delivery of Brain-Derived Neurotrophic Factor for Recovery After Stroke, E. Ho*, J. Obermeyer, A. Tuladhar, S. Payne, C. Morshead, M. Shoichet; University of Toronto, Toronto, ON, Canada

  • 11:45:00 AM 470. Compositional Control of pDNA/lPEI Nanoparticles Using Flash NanoComplexation to Improve in vivo Transfection Efficiency and Biocompatibility, Y. Hu*(1), H.-w. Liu(2), I. Minn(3), M. Pomper(3), H.-Q. Mao(1,2); (1)Johns Hopkins University School of Medicine, Baltimore, MD, USA, (2)Johns Hopkins University, Baltimore, MD, USA, (3)Johns Hopkins Medical Institutions, Baltimore, MD, USA

  • 12:00:00 PM 471. Tuning the Presentation and Density of Targeting Peptides on Polymeric Nanoparticles to Improve Bone Localization, M. Ackun-Farmmer*, Y. Yan, D. Fraser, D. Benoit; University of Rochester, Rochester, NY, USA

  • 12:15:00 PM 472. Towards a Nanoparticle-based Prophylactic for Maternal Autoantibody-related Autism, A. Bolandparvaz*, R. Harriman, N. Vapniarsky, K. Alvarez, Z. Zang, J. Van De Water, J. Lewis; University of California, Davis, Davis, CA, USA