Biomaterials for Therapeutic Drug Delivery 1

Timeslot: Friday, April 5, 2019 - 1:45pm to 3:45pm
Track: Therapeutic Delivery
Room: Skagit 2

About

Controlled release approaches have the potential to effectively treat a variety of medical conditions, while avoiding complications such as off-site toxicity and drug-resistance. Approaches can include localized, depot-based methods as well as targeted, systemic treatments. Controlled drug delivery can result from affinity interactions, bond cleavage, reservoir or diffusion-based control, and/or stimulus-responsive methodologies. This session will focus on the development of these drug delivery systems, which include nano and microparticles, hydrogels, scaffolds, and thin films, for applications including but not limited to regenerative medicine/tissue engineering, cancer, microbial infection, and autoimmune diseases.

Abstracts

Abstracts will be available for download on April 3, 2019.

  • 1:45:00 PM 409. Sustained Delivery of Glycogen Synthase Kinase Inhibitor AR28 Is Critical for Osteogenic Selectivity in MSCs, D. Benoit*(1,2), M. Newman(1,2), M. Ackun-Farmmer(1,2), Y. Wang(1,2), B. Xiao(1,2), J.E. Puzas(2); (1)University of Rochester, Rochester, NY, USA, (2)University of Rochester Medical Center, Rochester, NY, USA

  • 2:00:00 PM 410. Supramolecular PEGylation as an Innovative Approach to Biopharmaceutical Formulation and Delivery, E. Appel*, C. Maikawa, A. Smith; Stanford University, Stanford, CA, USA

  • 2:15:00 PM 411. Logical Stimuli-Triggered Delivery of Small Molecules from Hydrogel Biomaterials, C. DeForest*, E. Ruskowitz, M. Comerford, B. Badeau; University of Washington, Seattle, WA, USA

  • 2:30:00 PM 412. Assessment of Antioxidant Copolymers for Improved ROS Scavenging in Post Traumatic Osteoarthritis, A. Miskalis*(1,2), B. Dollinger(1), C. DeJulius(1), C. Duvall(1); (1)Vanderbilt University, Nashville, TN, USA, (2)Duquesne University, Pittsburgh, PA, USA

  • 2:45:00 PM 413. Biomimetic Apoptotic Erythrocyte Membrane-Coated Microparticles for Enhanced Tolerance Induction, K. Rhodes*, R. Meyer, C. State, J. Green; Johns Hopkins University, Baltimore, MD, USA

  • 3:00:00 PM 414. Polybubble Depots Functioning as a Theranostic-enabling Anti-cancer Platform Technology, S. Arun Kumar*, J. Good, D. Hendrix, W. Souery, Y.-Y. Jhan, C. Bishop; Texas A&M University, College Station, TX, USA

  • 3:15:00 PM 415. Design of Semi-Randomized Zwitterionic Peptides to Prevent Serum Aggregation of Polymeric Nanoparticles, C. Overby, III*(1), D. Benoit(1,2); (1)University of Rochester, Rochester, NY, USA, (2)University of Rochester Medical Center, Rochester, NY, USA

  • 3:30:00 PM 416. Nanofiber-based Opioid Bandages for Localized Treatment of Burn Pain, M. Skoff*(1), M. Patterson(1), J. Mao(2), Z. You(2), C. Tison(1); (1)Luna Innovations Incorporated, Charlottesville, VA, USA, (2)Massachusetts General Hospital, Boston, MA, USA